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Search Results for " angiogenesis inhibitor "

135

阻害剤

14

天然化合物

36

リコンビナントタンパク質

カタログ番号 製品名 別名 ターゲット
T71722 Angiogenesis inhibitor BT2
Angiogenesis inhibitor BT2 is a novel inhibitor of angiogenesis and vascular permeability, inhibiting ERK phosphorylation and the expression of FosB/ΔFosB, VCAM-1, and many genes involved in proliferation, migration, ang...
T74627 Angiogenesis inhibitor 3
Angiogenesis Inhibitor 3 (Compound 8) is a potent substance that effectively inhibits the growth of HUVEC and HCT-15 cells, demonstrating IC50 values of 1.00 and 0.71 μM, respectively. It not only induces apoptosis in th...
T83116 Angiogenesis inhibitor 4
Angiogenesis Inhibitor 4 is a potent agent for inhibiting angiogenesis, with potential applications in cancer research [1].
T9929 Ramucirumab VEGFR
Ramucirumab is a human VEGFR-2 antagonist for the treatment of solid tumors.
T9963 MPT0B390 HDAC
MPT0B390 is an inhibitor of HDAC and a TIMP3 inducer inhibiting tumor growth, metastasis, and angiogenesis.
T2427 EHop-016 EHop 016 Rho , Ras
EHop-016 is a specific Rac GTPase inhibitor with IC50 of 1.1 μM for Rac1 in MDA-MB-231 and MDA-MB-435 cells, equally effective inhibition for Rac3.
T22086 HA 155 Autotaxin Inhibitor IV PDE
HA 155 (Autotaxin Inhibitor IV) is a boronic acid-based compound, inhibiting ATX with IC50 of 5.7 nM by selectively binding to its catalytic threonine.
T6207 SC144 Apoptosis , Interleukin
SC144 is an orally active small-molecule gp130 inhibitor.
T4425 JK-P3 VEGFR
JK-P3 is a pyrazole-based inhibitor of VEGFR-2 (IC50: 7.8 μM). JK-P3 inhibits FGFR 1/3 kinase activity in vitro, but has no effect on FGFR signaling in cell-based assays. The compound blocks wound healing and tube format...
TQ0317 R1530 R-1530,R 1530 VEGFR , FGFR , FLT , PDGFR
R1530 is a multikinase inhibitor with antineoplastic and antiangiogenesis activities.
T6540 Ibuprofen Lysine Neoprofen COX
Ibuprofen Lysine (Neoprofen) is a non-steroidal anti-inflammatory drug.
T0314 Hexylresorcinol 4-Hexylresorcinol Apoptosis , Tyrosinase , Antibacterial , Parasite
Hexylresorcinol (4-Hexylresorcinol) is a substituted dihydroxybenzene used topically as an antiseptic for the treatment of minor skin infections.
T1394 Ibuprofen Brufen,(±)-Ibuprofe,Motrin,Advil COX
Ibuprofen (Advil) is a propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic effects. Ibuprofen inhibits the activity of cyclo-oxygenase I and II, resu...
T6351 MGCD-265 analog MGCD-265,Glesatinib Apoptosis , VEGFR , c-Met/HGFR
MGCD-265 analog (Glesatinib) is an orally bioavailable multitargeted tyrosine kinase inhibitor with potential antineoplastic activity with IC50 of 29 nM and 10 nM for c-Met and VEGFR2, respectively.
T2456 Tivozanib AV-951,KRN951 VEGFR , PDGFR , Ephrin Receptor
Tivozanib (KRN951) is an orally bioavailable inhibitor of vascular endothelial growth factor receptors (VEGFRs) 1, 2 and 3 with potential antiangiogenic and antineoplastic activities.
T2690 Tranilast MK 341,SB 252218 RAAS , Prostaglandin Receptor
Tranilast (SB 252218), an antiallergic drug, suppresses lipid mediator and cytokine release from inflammatory cells, therefore utilized in the treatment of allergic disorders.
T8491 Vorolanib CM082,X-82 VEGFR , PDGFR
Vorolanib (X-82) is an orally active VEGFR/PDGFR dual inhibitor.
T23127 PD-161570 PD 161570 EGFR , FGFR , PDGFR , Src
PD-161570 is a potent and ATP-competitive human FGF-1 receptor inhibitor with an IC50 of 39.9 nM and a Ki of 42 nM. PD-161570 also inhibits the PDGFR, EGFR and c-Src tyrosine kinases with IC50 values of 310 nM, 240 nM, a...
T35570 Chiauranib CS2164 c-Fms , VEGFR , FLT , PDGFR , c-Kit , Aurora Kinase
Chiauranib is a multi-target inhibitor against tumor angiogenesis and exhibits potent anticancer effects. Chiauranib potently inhibits the angiogenesis-related kinases (VEGFR1, VEGFR2, VEGFR3, PDGFRα and c-Kit), mitosis-...
T13238 Tyrphostin AG1433 SU1433,AG1433 VEGFR , PDGFR
T2586 Cabozantinib XL184,BMS-907351 Apoptosis , VEGFR , FLT , c-Met/HGFR , c-RET , TAM Receptor , c-Kit
Cabozantinib (XL184) is a multi-targeted tyrosine kinase receptor inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt3 (IC50=0.035/1.3/4.6/7/11.3 nM). Cabozantinib exhibits both antitumor and antiangiogenic activity...
T5164 Cabozantinib hydrochloride XL184,Cabozantinib hydrochloride (849217-68-1(free base)),BMS-907351 VEGFR , FLT , c-Met/HGFR , TAM Receptor , c-Kit , ROR
Cabozantinib hydrochloride (XL184) is a potent pan-tyrosine kinases inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt4 (IC50s: 0.035, 1.3, 4.6, 7 and 6 nM).
T26254 Teglarinad chloride GMX 1777 chloride,EB1627,GMX1777,GMX1777 chloride,GMX 1777,GMX-1777 chloride,EB-1627,EB-1627 chloride,EB1627 chloride NAMPT
Teglarinad chloride (GMX-1777 chloride) is a potent inhibitor of NAMPT, the precursor of GMX1778.Teglarinad chloride has antitumor activity and acts by interfering with DNA repair and inhibiting angiogenesis.
T13050 SYP-5 HIF/HIF Prolyl-Hydroxylase , HIF
SYP-5 is a novel inhibitor of HIF-1, suppresses tumor cells invasion and angiogenesis.
T15574 Incyclinide COL-3,CMT-3 MMP
Incyclinide (COL-3) is a matrix metalloproteinase (MMP) inhibitor. Thereby causing extracellular matrix degradation, tumor growth and invasion, and inhibiting angiogenesis, and metastasis.
T37078 VEGFR-2-IN-6 VEGFR
VEGFR-2-IN-6 (WO 02/059110, example 64) is a potent inhibitor of VEGFR2, a crucial receptor involved in the regulation of angiogenesis [1].
T28077 MMPP VEGFR , STAT
MMPP is a novel VEGFR2 inhibitor with anti-inflammatory and potential anticancer activity, inhibits STAT3, inhibits angiogenesis via VEGFR2/AKT/ERK/NF-kappaB pathway, and can be used to alleviate myocardial injury.
T9127 MYLS22 Others
MYLS22 is a first-in-class and selective inhibitor of optic atrophy 1 (OPA1) . MYLS22 can target endothelial OPA1 to curtail tumor growth and inhibits angiogenesis by impinging on NFkB activity and on angiogenic gene exp...
T17105 TM6089 HIF/HIF Prolyl-Hydroxylase
TM6089 is an inhibitor of Prolyl Hydroxylase that stimulates HIF activity without iron chelation, induces angiogenesis, and protects organ against ischemia.
T6011 Batimastat BB94 MMP
Batimastat (BB94) (BB-94) is an effective, broad-spectrum matrix metalloprotease (MMP) inhibitor. Batimastat induces extracellular matrix degradation and inhibits angiogenesis, tumor growth and invasion, and metastasis.
T1895 SKLB 610 VEGFR , FGFR , PDGFR
SKLB610, a novel multi-targeted inhibitor, inhibits angiogenesis-related tyrosine kinase VEGFR2, FGFR2, and PDGFR at a rate of 97%, 65%, and 55%, respectively, at the concentration of 10 μM in biochemical kinase assays.
T4435 E7820 ER68203-00 Integrin
E7820 (ER68203-00) is an angiogenesis inhibitor by suppressing integrin a2 (a cell adhesion molecule expressed on endothelial cells).
T79860 TIE-2/VEGFR-2 kinase-IN-5 VEGFR , Tie-2
TIE-2/VEGFR-2 kinase-IN-5 is a potent TIE-2 and VEGFR-2 tyrosine kinase receptor inhibitor with anti-angiogenic activity and is commonly used in biomedical research related to angiogenesis.
T4235 Roblitinib FGF-401 FGFR
Roblitinib (FGF-401) is an inhibitor of human fibroblast growth factor receptor 4 (FGFR4), with potential antineoplastic activity. Upon administration, Roblitinib binds to and inhibits the activity of FGFR4, which leads ...
T2288 Motesanib AMG 706 VEGFR , c-Kit
Motesanib (AMG 706) is an orally bioavailable receptor tyrosine kinase inhibitor with potential antineoplastic activity. AMG 706 selectively targets and inhibits vascular endothelial growth factor (VEGFR), platelet-deriv...
T11556 HET0016 Others
HET0016 is a potent and selective 20-HETE synthase inhibitor (IC50s: 17.7 nM, 12.1 nM, and 20.6 nM for recombinant CYP4A1-, CYP4A2- and CYP4A3-catalyzed 20-HETE synthesis). HET0016 also is a selective CYP450 inhibitor, w...
T8554 KCC-07 DNA Alkylator/Crosslinker
KCC-07 is a selective, potent and brain-penetrant inhibitor of methyl-CpG-binding domain protein 2(MBD2) with anticancer activity. KCC-07 prevents binding of MBD2 to methylated DNA and activates brain specific angiogenes...
T24997 ABT-510 acetate ABT 510 acetate Apoptosis
ABT-510 acetate is an endogenous anti-angiogenic TSP peptide inhibitor, a thrombospondin analog, with anti-inflammatory, anti-cancer and anti-angiogenic activity that induces apoptosis and inhibits ovarian tumor growth i...
T3980 Su1498 Tyrphostin SU 1498,AG 1498 VEGFR
Su1498 (Tyrphostin SU 1498) is a selective inhibitor of the receptor tyrosine kinase VEGF receptor 2 (VEGFR2, aka FLK1; IC50 = 700 nM), having negligible activity at several other serine/threonine and tyrosine kinases.1,...
T1777 Nintedanib BIBF 1120,Intedanib VEGFR , FGFR , FLT , PDGFR , Src
Nintedanib (Intedanib) is a triple vascular kinase inhibitor that inhibits VEGFR1, VEGFR2, and VEGFR3 (IC50=34/13/13 nM), FGFR1, FGFR2, and FGFR3 (IC50=69/37/108 nM), PDGFRα, and PDGFRβ (IC50=59/65 nM). Nintedanib has an...
T2624 OSI-930 OSI 930 Apoptosis , c-Fms , Raf , VEGFR , FLT , CSF-1R , Src , c-Kit
OSI-930, an orally active inhibitor of c-Kit and the vascular endothelial growth factor receptor-2 (VEGFR-2), targets cancer cell proliferation and blood vessel growth (angiogenesis) in tumors.
T0097L Pazopanib GW786034 VEGFR , FGFR , PDGFR , c-Kit , Autophagy
Pazopanib (GW786034), a small molecule inhibitor, inhibits multiple protein tyrosine kinases with potential antineoplastic activity. Pazopanib selectively inhibits VEGFR-1, -2 and -3, c-kit and PDGF-R, which may result i...
T2576 Brivanib (alaninate) BMS-582664,Brivanib Alaninate VEGFR , FGFR , Autophagy
Brivanib Alaninate (BMS-582664) is the alaninate salt of a vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor with potential antineoplastic activity. Brivanib strongly binds to and inhibits VEGFR2, a tyrosi...
T3211 Midostaurin N-Benzoylstaurosporine,PKC412,CGP41231,CGP 41251 Others , PKC
PKC412(Midostaurin (PKC412); CGP41231; CGP41251) is a broad spectrum protein kinase inhibitor. Midostaurin inhibits protein kinase C alpha (PKCalpha), vascular endothelial growth factor receptor 2 (VEGFR2), c-kit, platel...
T21872 CCT018159 Apoptosis , HSP
CCT018159 is a 3,4-diarylpyrazole resorcinol, an ATP-competitive HSP90ATPase inhibitor that inhibits human Hsp90β and yeast Hsp90 with IC50s of 3.2 and 6.6 μM, respectively.CCT018159 inhibits key endothelial and tumor ce...
T6517 Golvatinib E-7050 VEGFR , c-Met/HGFR
Golvatinib (E-7050) is an orally bioavailable dual kinase inhibitor of c-Met (hepatocyte growth factor receptor) and VEGFR-2 (vascular endothelial growth factor receptor-2) tyrosine kinases with potential antineoplastic ...
TP1345 Kisspeptin-10, human (TFA)(374675-21-5,FREE) GPR , Kisspeptin
Kisspeptin-10, human TFA is a potent vasoconstrictor and angiogenesis inhibitor. Kisspeptin-10, human TFA acts as a tumor metastasis suppressor via its receptor GPR54. Kisspeptin-10-GPR54 system plays an important role i...
T67836 AT-533 HSP , HSV
AT-533 is a potent inhibitor of Hsp90 and HSV. AT-533 blocks the HIF-1α/VEGF/VEGFR-2 signaling pathway, leading to suppress tumor growth and angiogenesis. AT-533 also inhibits the activation of the downstream pathways, i...
T63505 Tivozanib hydrochloride hydrate
Tivozanib hydrochloride hydrate is a selective, potent, orally active VEGFR tyrosine kinase inhibitor that acts on VEGFR-1 (IC50: 0.21 nM), VEGFR-2 (IC50: 0.16 nM), and VEGFR-3 (IC50: 0.24 nM). Tivozanib hydrochloride hy...
T1852 Rac-Belinostat NSC726630,PXD101,PX-105684 HDAC
Rac-Belinostat (PX-105684) is a novel hydroxamic acid-type histone deacetylase (HDAC) inhibitor with antineoplastic activity. Belinostat targets HDAC enzymes, thereby inhibiting tumor cell proliferation, inducing apoptos...

Compounds

Angiogenesis inhibitor BT2
T71722
Synonym:
Target:
Angiogenesis inhibitor 3
T74627
Synonym:
Target:
Angiogenesis inhibitor 4
T83116
Synonym:
Target:
Ramucirumab
T9929
Synonym:
Target: VEGFR
MPT0B390
T9963
Synonym:
Target: HDAC
EHop-016
T2427
Synonym: EHop 016
Target: Rho, Ras
HA 155
T22086
Synonym: Autotaxin Inhibitor IV
Target: PDE
SC144
T6207
Synonym:
Target: Apoptosis, Interleukin
JK-P3
T4425
Synonym:
Target: VEGFR
R1530
TQ0317
Synonym: R-1530,R 1530
Target: VEGFR, FGFR, FLT, PDGFR
Ibuprofen Lysine
T6540
Synonym: Neoprofen
Target: COX
Hexylresorcinol
T0314
Synonym: 4-Hexylresorcinol
Target: Apoptosis, Tyrosinase, Antibacterial, Parasite
Ibuprofen
T1394
Synonym: Brufen,(±)-Ibuprofe,Motrin,Advil
Target: COX
MGCD-265 analog
T6351
Synonym: MGCD-265,Glesatinib
Target: Apoptosis, VEGFR, c-Met/HGFR
Tivozanib
T2456
Synonym: AV-951,KRN951
Target: VEGFR, PDGFR, Ephrin Receptor
Tranilast
T2690
Synonym: MK 341,SB 252218
Target: RAAS, Prostaglandin Receptor
Vorolanib
T8491
Synonym: CM082,X-82
Target: VEGFR, PDGFR
PD-161570
T23127
Synonym: PD 161570
Target: EGFR, FGFR, PDGFR, Src
Chiauranib
T35570
Synonym: CS2164
Target: c-Fms, VEGFR, FLT, PDGFR, c-Kit, Aurora Kinase
Tyrphostin AG1433
T13238
Synonym: SU1433,AG1433
Target: VEGFR, PDGFR
Cabozantinib
T2586
Synonym: XL184,BMS-907351
Target: Apoptosis, VEGFR, FLT, c-Met/HGFR, c-RET, TAM Receptor, c-Kit
Cabozantinib hydrochloride
T5164
Synonym: XL184,Cabozantinib hydrochloride (849217-68-1(free base)),BMS-907351
Target: VEGFR, FLT, c-Met/HGFR, TAM Receptor, c-Kit, ROR
Teglarinad chloride
T26254
Synonym: GMX 1777 chloride,EB1627,GMX1777,GMX1777 chloride,GMX 1777,GMX-1777 chloride,EB-1627,EB-1627 chloride,EB1627 chloride
Target: NAMPT
SYP-5
T13050
Synonym:
Target: HIF/HIF Prolyl-Hydroxylase, HIF
Incyclinide
T15574
Synonym: COL-3,CMT-3
Target: MMP
VEGFR-2-IN-6
T37078
Synonym:
Target: VEGFR
MMPP
T28077
Synonym:
Target: VEGFR, STAT
MYLS22
T9127
Synonym:
Target: Others
TM6089
T17105
Synonym:
Target: HIF/HIF Prolyl-Hydroxylase
Batimastat
T6011
Synonym: BB94
Target: MMP
SKLB 610
T1895
Synonym:
Target: VEGFR, FGFR, PDGFR
E7820
T4435
Synonym: ER68203-00
Target: Integrin
TIE-2/VEGFR-2 kinase-IN-5
T79860
Synonym:
Target: VEGFR, Tie-2
Roblitinib
T4235
Synonym: FGF-401
Target: FGFR
Motesanib
T2288
Synonym: AMG 706
Target: VEGFR, c-Kit
HET0016
T11556
Synonym:
Target: Others
KCC-07
T8554
Synonym:
Target: DNA Alkylator/Crosslinker
ABT-510 acetate
T24997
Synonym: ABT 510 acetate
Target: Apoptosis
Su1498
T3980
Synonym: Tyrphostin SU 1498,AG 1498
Target: VEGFR
Nintedanib
T1777
Synonym: BIBF 1120,Intedanib
Target: VEGFR, FGFR, FLT, PDGFR, Src
OSI-930
T2624
Synonym: OSI 930
Target: Apoptosis, c-Fms, Raf, VEGFR, FLT, CSF-1R, Src, c-Kit
Pazopanib
T0097L
Synonym: GW786034
Target: VEGFR, FGFR, PDGFR, c-Kit, Autophagy
Brivanib (alaninate)
T2576
Synonym: BMS-582664,Brivanib Alaninate
Target: VEGFR, FGFR, Autophagy
Midostaurin
T3211
Synonym: N-Benzoylstaurosporine,PKC412,CGP41231,CGP 41251
Target: Others, PKC
CCT018159
T21872
Synonym:
Target: Apoptosis, HSP
Golvatinib
T6517
Synonym: E-7050
Target: VEGFR, c-Met/HGFR
Kisspeptin-10, human (TFA)(374675-21-5,FREE)
TP1345
Synonym:
Target: GPR, Kisspeptin
AT-533
T67836
Synonym:
Target: HSP, HSV
Tivozanib hydrochloride hydrate
T63505
Synonym:
Target:
Rac-Belinostat
T1852
Synonym: NSC726630,PXD101,PX-105684
Target: HDAC
1 2 3
カタログ番号 製品名 別名 ターゲット
T3860 Isoliquiritin apioside MMP , p38 MAPK , NF-κB
Isoliquiritin apioside, isolated from Glycyrrhizae radix rhizome, significantly decreases PMA-induced increases in MMP9 activities and suppresses PMA-induced activation of MAPK and NF-κB. Isoliquiritin apioside auppresse...
T6670 Silymarin Silybin B SARS-CoV
Silymarin (Silybin B) (Silybin B) is a polyphenolic flavonoid that extracts from the milk thistle or seeds of Silybum marianum. It is used in the prevention and treatment of liver diseases.
T0724 Formononetin Biochanin B,Flavosil,Formononetol Apoptosis , FGFR
Formononetin (Flavosil) is an O-methylated isoflavone and a phytoestrogen from the root of Astragalus membranaceus.
T8846 Beta-Escin B-escin,AESCINE Immunology/Inflammation related
beta-Escin is a natural mixture of triterpenoid saponins isolated from horse chestnut (Aesculus hippocastanum) seeds, can be used as a vasoprotective anti-inflammatory, anti-edematous and anti-nociceptive agent.
T4586 (Rac)-Arnebin 1 beta, beta-dimethylacrylshikonin Others
(Rac)-Arnebin 1 (beta, beta-dimethylacrylshikonin) has anti-tumor, anti-inflammatory, anti-immune deficiency and protecting liver.
T7203 Oglufanide L-Glutamyl-L-tryptophan,H-Glu-Trp-OH VEGFR , HCV Protease , Endogenous Metabolite
Oglufanide (H-Glu-Trp-OH) is a naturally occurring thymic immunomodulator,and inhibits vascular endothelial growth factor (VEGF).
T3250 Royal Jelly acid 10-Hydroxy-trans-2-decenoic acid,10-Hydroxy-2-decenoic acid,10H2DA,10-Hydroxy-2-decylenic acid,Queen Bee Acid,(E)-10-Hydroxy-2-decenoic acid VEGFR , Endogenous Metabolite
Royal Jelly acid (Queen Bee Acid) is an inhibitor of VEGF-induced angiogenesis, cell migration and proliferation.
T3229 Cytochalasin D ATPase , p38 MAPK , Calcium Channel , Akt , PI3K
Cytochalasin D is an actin inhibitor, the removal of actin stress fibers is crucial for the chondrogenic differentiation. It may be an inhibitor of some fertilization processes such as sperm penetration or sperm head dec...
T6S1487 Ginsenoside Rg5 NF-κB , COX , IGF-1R
1. Ginsenoside Rg5 could be a beneficial agent for the treatment of Alzheimer's disease. 2. Ginsenoside Rg5 suppresses LPS-induced nitric oxide (NO) production and proinflammatory TNF-α secretion. 3. Ginsenoside Rg5 can ...
T21005 Lupulon
Lupulon has a role as an apoptosis inducer, antimicrobial agent, angiogenesis inhibitor, and antineoplastic agent.
T26369 (+/-)-Marmesin Marmesin,(S)-Marmesin
Marmesin is a novel angiogenesis inhibitor.
T23773 Barbigerone Barubigeron
Barbigerone is a tumor angiogenesis, growth, and metastasis inhibitor in melanoma.
TN1755 Hyperforin 5-HT Receptor , COX
Hyperforin acts as an angiogenesis inhibitor, it as a possible antidepressant component of hypericum extracts.
T35577 Phosphatidylserines (bovine)
Phosphatidylserine is a naturally occurring phospholipid that comprises 2-10% of total phospholipids in mammals and is enriched in the central nervous system, particularly the retina. It is anionic and found mainly on th...

Recombinant Proteins

カタログ番号 製品名 Species Expression System
TMPJ-00685 BAI3 Protein, Human, Recombinant (His) Human Human Cells
Human Brain-Specific Angiogenesis Inhibitor 3 (BAI3) is a 177 kDa seven-span transmembrane (TM) protein, which is thought to be a member of the secretin receptor family. It is synthesized by neurons of the CNS and likely...
TMPJ-00603 TL1A/TNFSF15 Protein, Mouse, Recombinant Mouse E. coli
Tumor Necrosis Factor Ligand Superfamily Member 15 (TNFSF15) is a new member of the tumor necrosis factor family. TNFSF15 is predominantly an endothelial cell-specific gene, and recombinant TNFSF15 is a potent inhibitor ...
TMPY-04645 TL1A/TNFSF15 Protein, Human, Recombinant (hFc) Human HEK293
TL1A, also known as TNFSF15, is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. It is specifically expressed in endothelial cells. TL1A also can be detected in monocytes, placenta, lung, liver, ...
TMPY-02450 Cathepsin D Protein, Human, Recombinant (His) Human HEK293
Cathepsin D (CTSD), a well known lysosomal aspartyl protease and belongs to the peptidase C1 family, which is a normal and major component of lysosomes, and is found in almost all cells and tissues of mammals. Its mostly...
TMPH-02927 Tenomodulin Protein, Mouse, Recombinant (His) Mouse E. coli
May be an angiogenesis inhibitor.
TMPH-01566 Isthmin-1/ISM1 Protein, Human, Recombinant (His) Human E. coli
Acts as an angiogenesis inhibitor.
TMPH-02263 VASH1 Protein, Human, Recombinant (His) Human E. coli
Tyrosine carboxypeptidase that removes the C-terminal tyrosine residue of alpha-tubulin, thereby regulating microtubule dynamics and function. Critical for spindle function and accurate chromosome segregation during mito...
TMPY-00266 PEDF Protein, Rat, Recombinant (His) Rat HEK293
Pigment epithelium-derived factor, also known as PEDF, Serpin F1, and SERPINF1, is a multiple functional protein that has both anti-angiogenic activity and neurotrophic activity at the same time. PEDF is a secreted glyco...
TMPY-01112 PEDF Protein, Mouse, Recombinant (His) Mouse HEK293
Pigment epithelium-derived factor, also known as PEDF, Serpin F1, and SERPINF1, is a multiple functional protein that has both anti-angiogenic activity and neurotrophic activity at the same time. PEDF is a secreted glyco...
TMPY-01328 PEDF Protein, Human, Recombinant (His) Human HEK293
Pigment epithelium-derived factor, also known as PEDF, Serpin F1, and SERPINF1, is a multiple functional protein that has both anti-angiogenic activity and neurotrophic activity at the same time. PEDF is a secreted glyco...
TMPY-01484 THSD1 Protein, Mouse, Recombinant (His) Mouse HEK293
Thrombospondin type-1 domain-containing protein 1, also known as transmembrane molecule with thrombospondin module, THSD1 and TMTSP, is a single-pass type I membrane protein that contains one TSP type-1 domain. THSD1 is ...
TMPY-05802 TL1A/TNFSF15 Protein, Human, Recombinant (His) Human HEK293
TL1A, also known as TNFSF15, is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. It is specifically expressed in endothelial cells. TL1A also can be detected in monocytes, placenta, lung, liver, ...
TMPY-04978 TL1A/TNFSF15 Protein, Human, Recombinant (rFc) Human HEK293
TL1A, also known as TNFSF15, is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. It is specifically expressed in endothelial cells. TL1A also can be detected in monocytes, placenta, lung, liver, ...
TMPY-04979 TL1A/TNFSF15 Protein, Human, Recombinant (mFc) Human HEK293
TL1A, also known as TNFSF15, is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. It is specifically expressed in endothelial cells. TL1A also can be detected in monocytes, placenta, lung, liver, ...
TMPY-03067 TL1A/TNFSF15 Protein, Rat, Recombinant (hFc) Rat HEK293
TL1A, also known as TNFSF15, is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. It is specifically expressed in endothelial cells. TL1A also can be detected in monocytes, placenta, lung, liver, ...
TMPJ-00948 Endostatin Protein, Mouse, Recombinant (His) Mouse Human Cells
Endostatin, an endogenous non‑glycosylated inhibitor of endothelial cell proliferation and angiogenesis. It is produced and/or trimmed by metalloproteinases such as MMP‑2 and MMP‑9, and cathepsins S, B and L. The N‑termi...
TMPJ-00265 Serpin F1 Protein, Mouse, Recombinant Mouse E. coli
Serpin F1 is secreted Neurotrophic protein and belongs to the serpin family. Serpin F1 Highly expressed in the liver, gastric glandular mucosa and renal tubules. It is also expressed in the brain, heart, lung retina and ...
TMPJ-00929 Serpin B3 Protein, Human, Recombinant (N-His) Human E. coli
Serpin B3, also known as squamous cell carcinoma antigen-1 (SCCA-1), is a member of the serpin superfamily of serine protease inhibitors. Serpin B3 belongs to the subgroup ovalbumin-related serpins which are involved in ...
TMPJ-00928 Serpin B3 Protein, Human, Recombinant (C-His) Human Human Cells
Serpin B3, also known as squamous cell carcinoma antigen-1 (SCCA-1), is a member of the serpin superfamily of serine protease inhibitors. Serpin B3 belongs to the subgroup ovalbumin-related serpins which are involved in ...
TMPY-00733 Cathepsin D Protein, Mouse, Recombinant (His) Mouse HEK293
Cathepsin D (CTSD), a well known lysosomal aspartyl protease and belongs to the peptidase C1 family, which is a normal and major component of lysosomes, and is found in almost all cells and tissues of mammals. Its mostly...
TMPY-01841 Serpin I2 Protein, Human, Recombinant (His) Human HEK293
Serpins are the largest and most diverse family of serine protease inhibitors which are involved in some fundamental biological processes such as blood coagulation, complement activation, fibrinolysis, angiogenesis, infl...
TMPH-01870 Plasminogen Protein, Human, Recombinant (His) Human E. coli
Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the...
TMPJ-00916 TIMP-2 Protein, Mouse, Recombinant (His) Mouse Human Cells
Mouse Metalloproteinase inhibitor 2(TIMP-2), belongs to a family of proteins that regulate the activation and proteolytic activity of matrix metalloproteinases (MMPs). There are four mammalian members of the family; TIMP...
TMPY-01711 Serpin B2 Protein, Human, Recombinant (GST) Human Baculovirus-Insect Cells
Serpins are the largest and most diverse family of serine protease inhibitors which are involved in some fundamental biological processes such as blood coagulation, complement activation, fibrinolysis, angiogenesis, infl...
TMPJ-00490 Serpin A5 Protein, Human, Recombinant (His) Human Human Cells
Serpin A5 is a member of the human Serpin superfamily consists of at least 35 members. It is synthesized in the liver and has been detected in saliva, cerebral spinal fluid, amniotic fluid, tears and semen. As a potent i...
TMPY-02329 TFPI2 Protein, Mouse, Recombinant (His) Mouse HEK293
Tissue factor pathway inhibitor-2 (TFPI2), a member of the Kunitz-type serine proteinase inhibitor family, is a structural homologue of tissue factor pathway inhibitor (TFPI). It is a 32 kDa matrix-associated glycoprotei...
TMPY-01004 TFPI2 Protein, Human, Recombinant (His) Human HEK293
Tissue factor pathway inhibitor-2 (TFPI2), a member of the Kunitz-type serine proteinase inhibitor family, is a structural homologue of tissue factor pathway inhibitor (TFPI). It is a 32 kDa matrix-associated glycoprotei...
TMPY-02859 TFPI2 Protein, Mouse, Recombinant (hFc) Mouse HEK293
Tissue factor pathway inhibitor-2 (TFPI2), a member of the Kunitz-type serine proteinase inhibitor family, is a structural homologue of tissue factor pathway inhibitor (TFPI). It is a 32 kDa matrix-associated glycoprotei...
TMPY-01551 Serpin B8 Protein, Mouse, Recombinant (His) Mouse Baculovirus-Insect Cells
Serpins are the largest and most diverse family of serine protease inhibitors which are involved in a number of fundamental biological processes such as blood coagulation, complement activation, fibrinolysis, angiogenesi...
TMPY-01589 Serpin B10 Protein, Mouse, Recombinant (His) Mouse Baculovirus-Insect Cells
Serpins are the largest and most diverse family of serine protease inhibitors which are involved in a number of fundamental biological processes such as blood coagulation, complement activation, fibrinolysis, angiogenesi...
TMPJ-00681 EDIL3 Protein, Human, Recombinant (His) Human Human Cells
EGF-Like Repeat and Discoidin I-Like Domain-Containing Protein 3 (EDIL3) is a 52 kDa extracellular matrix protein that is expressed by endothelial tissues during embryonic vascular development. EDIL3 becomes quiescent at...
TMPJ-01166 IGFBP-7 Protein, Mouse, Recombinant (His) Mouse Human Cells
Insulin-like growth factor-binding protein 7(IGFBP-7) is a secreted glycosylated protein that contains three protein domain modules. IGFBP7 contains an N-terminal IGFBP domain, followed by a Kazal-type serine proteinase ...
TMPY-01632 Serpin B4 Protein, Mouse, Recombinant (His) Mouse Baculovirus-Insect Cells
Serpins are the largest and most diverse family of serine protease inhibitors which are involved in a number of fundamental biological processes such as blood coagulation, complement activation, fibrinolysis, angiogenesi...
TMPY-04501 Angiotensinogen Protein, Rat, Recombinant (His) Rat HEK293
Angiotensinogen, also known as AGT and SerpinA8, is a member of the serpin family. It is an α-2-globulin that is produced constitutively and released into the circulation mainly by the liver. Angiotensinogen is a essenti...
TMPY-02232 Angiotensinogen Protein, Mouse, Recombinant (His) Mouse HEK293
Angiotensinogen, also known as AGT and SerpinA8, is a member of the serpin family. It is an α-2-globulin that is produced constitutively and released into the circulation mainly by the liver. Angiotensinogen is a essenti...
TMPY-01232 Angiotensinogen Protein, Human, Recombinant (His) Human HEK293
Angiotensinogen, also known as AGT and SerpinA8, is a member of the serpin family. It is an α-2-globulin that is produced constitutively and released into the circulation mainly by the liver. Angiotensinogen is a essenti...
BAI3 Protein, Human, Recombinant (His)
TMPJ-00685
Species: Human
Expression System: Human Cells
TL1A/TNFSF15 Protein, Mouse, Recombinant
TMPJ-00603
Species: Mouse
Expression System: E. coli
TL1A/TNFSF15 Protein, Human, Recombinant (hFc)
TMPY-04645
Species: Human
Expression System: HEK293
Cathepsin D Protein, Human, Recombinant (His)
TMPY-02450
Species: Human
Expression System: HEK293
Tenomodulin Protein, Mouse, Recombinant (His)
TMPH-02927
Species: Mouse
Expression System: E. coli
Isthmin-1/ISM1 Protein, Human, Recombinant (His)
TMPH-01566
Species: Human
Expression System: E. coli
VASH1 Protein, Human, Recombinant (His)
TMPH-02263
Species: Human
Expression System: E. coli
PEDF Protein, Rat, Recombinant (His)
TMPY-00266
Species: Rat
Expression System: HEK293
PEDF Protein, Mouse, Recombinant (His)
TMPY-01112
Species: Mouse
Expression System: HEK293
PEDF Protein, Human, Recombinant (His)
TMPY-01328
Species: Human
Expression System: HEK293
THSD1 Protein, Mouse, Recombinant (His)
TMPY-01484
Species: Mouse
Expression System: HEK293
TL1A/TNFSF15 Protein, Human, Recombinant (His)
TMPY-05802
Species: Human
Expression System: HEK293
TL1A/TNFSF15 Protein, Human, Recombinant (rFc)
TMPY-04978
Species: Human
Expression System: HEK293
TL1A/TNFSF15 Protein, Human, Recombinant (mFc)
TMPY-04979
Species: Human
Expression System: HEK293
TL1A/TNFSF15 Protein, Rat, Recombinant (hFc)
TMPY-03067
Species: Rat
Expression System: HEK293
Endostatin Protein, Mouse, Recombinant (His)
TMPJ-00948
Species: Mouse
Expression System: Human Cells
Serpin F1 Protein, Mouse, Recombinant
TMPJ-00265
Species: Mouse
Expression System: E. coli
Serpin B3 Protein, Human, Recombinant (N-His)
TMPJ-00929
Species: Human
Expression System: E. coli
Serpin B3 Protein, Human, Recombinant (C-His)
TMPJ-00928
Species: Human
Expression System: Human Cells
Cathepsin D Protein, Mouse, Recombinant (His)
TMPY-00733
Species: Mouse
Expression System: HEK293
Serpin I2 Protein, Human, Recombinant (His)
TMPY-01841
Species: Human
Expression System: HEK293
Plasminogen Protein, Human, Recombinant (His)
TMPH-01870
Species: Human
Expression System: E. coli
TIMP-2 Protein, Mouse, Recombinant (His)
TMPJ-00916
Species: Mouse
Expression System: Human Cells
Serpin B2 Protein, Human, Recombinant (GST)
TMPY-01711
Species: Human
Expression System: Baculovirus-Insect Cells
Serpin A5 Protein, Human, Recombinant (His)
TMPJ-00490
Species: Human
Expression System: Human Cells
TFPI2 Protein, Mouse, Recombinant (His)
TMPY-02329
Species: Mouse
Expression System: HEK293
TFPI2 Protein, Human, Recombinant (His)
TMPY-01004
Species: Human
Expression System: HEK293
TFPI2 Protein, Mouse, Recombinant (hFc)
TMPY-02859
Species: Mouse
Expression System: HEK293
Serpin B8 Protein, Mouse, Recombinant (His)
TMPY-01551
Species: Mouse
Expression System: Baculovirus-Insect Cells
Serpin B10 Protein, Mouse, Recombinant (His)
TMPY-01589
Species: Mouse
Expression System: Baculovirus-Insect Cells
EDIL3 Protein, Human, Recombinant (His)
TMPJ-00681
Species: Human
Expression System: Human Cells
IGFBP-7 Protein, Mouse, Recombinant (His)
TMPJ-01166
Species: Mouse
Expression System: Human Cells
Serpin B4 Protein, Mouse, Recombinant (His)
TMPY-01632
Species: Mouse
Expression System: Baculovirus-Insect Cells
Angiotensinogen Protein, Rat, Recombinant (His)
TMPY-04501
Species: Rat
Expression System: HEK293
Angiotensinogen Protein, Mouse, Recombinant (His)
TMPY-02232
Species: Mouse
Expression System: HEK293
Angiotensinogen Protein, Human, Recombinant (His)
TMPY-01232
Species: Human
Expression System: HEK293